Pros/Cons of Freestyle Libre 2: Is Flash a Good Match for My Family?
Michelle MacPhee
D-Mom, M.S. (Psychology)
What makes Libre a worthwhile addition to our family’s diabetes management toolbox? Through personal experience, we have learned a lot about this flash glucose monitoring system - about its benefits, as well as its drawbacks. We break down the Libre and Libre 2 systems for you here with details on their features and function, to help you figure out which system best fits your family's needs and priorities.
As a protective d-mom, I wore a sensor (though I don’t have diabetes myself) to try out the system before our 10-year-old son (who does have T1D). I was impressed by how convenient it was! Our son was resistant about trying it out at first… he’s fed up with all things diabetes right now and didn’t want to give another d-tech device the time of day… until he saw me scan once. Then he was hooked. Here's my thoughts on Libre / Libre 2...
Measures glucose levels just beneath the skin, used by people who have diabetes. Designed as an alternative to fingerstick monitoring, to get a glucose reading you just “scan” a glucose sensor, without have to poke each time you check. This gives you a measure of the glucose in the interstitial fluid at the sensor. The only Flash Glucose Monitoring systems available right now in Canada are the Freestyle Libre and Libre 2.
Background reading on Libre/Libre 2:
Top 6 Benefits of Freestyle Libre:
1. Glucose Alerts are now available with Libre 2
As the "next generation of flash glucose monitoring," Libre 2 also now provides optional, real-time glucose alarms for flash users, even before you scan. The sensor is checking glucose every minute, and if the reading is outside of your target range, these alarms will let you know.
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Low Glucose Alert
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High Glucose Alert
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Signal Loss Alert
This feature was not available with the original Libre system. It represents a significant improvement in the technology, as you don't have to scan the sensor in order to know (in real-time) if your child's glucose has dropped too low. This provides a safety net and peace of mind if your child doesn’t recognize his own lows, or is easily distracted from feeling the symptoms if he's exercising or playing videogames.
More on Libre 2 Alarms:
2. Replaces Most Fingerpokes
If you have used a Continuous Glucose Monitor (CGM) then you’re familiar with the simplicity of knowing your current glucose level at a glance. Flash Glucose Monitoring systems (both Libre and Libre 2) offer the same ease: glucose checks are quick, convenient and painless. All you need to do is pass the reader over the sensor to “scan” it, wait 1 second for processing, and your current glucose reading pops up on the screen. For most of the glucose checks done in a day, Flash Monitoring eliminates the need to wash hands, get a strip, put the strip in, wait for the meter to be ready, poke your finger with a lancet, apply the blood drop, and wait 4-6 seconds for the meter to process the sample and display the result. In addition, you don’t need to calibrate the system with a fingerstick meter check, like you do with some CGM systems. In fact, Libre/Libre 2 comes factory-calibrated, there’s no way to enter an independent calibration number. (I can imagine that this could create an issue when the system is not reading accurately for an extended period, as there’s nothing you can do to correct it, but our family hasn’t yet come across that problem.) There are situations in which a fingerstick BG check is still recommended (see Limitations of Libre, below), but the bottom line is that Flash replaces most fingerstick checks.
Tip from the Trenches
This was the biggest bonus for my 10-year old son. When he’s wearing a sensor he doesn’t have to leave the fun, go do the prep work, poke his finger… all he has to do is swipe and read the result. This is a huge benefit at school in particular: scanning means he doesn’t have to “waste time” checking his glucose while all his friends run outside for recess; he no longer lags a few minutes behind his friends when they start eating lunch. This can have a bonus side-effect of lifting the emotional burden of diabetes a bit. And sometimes a “bit” means a lot.
-Michelle
3. Back-Data
When you use a meter for a BG check, you get a single data point: your blood glucose reading in this moment. Flash glucose monitoring (both Libre and Libre 2), however, in addition to telling you the current glucose reading at the moment that you scan the sensor, also displays a graph of the glucose readings for the past 8 hours, whether or not you scanned the sensor previously during that time. This is because the sensor continuously measures glucose, automatically storing the reading every 15 minutes*. The data then becomes available to you when you scan.
This is useful for a few reasons:
First, you don’t have to think about it; the sensor is taking and storing the readings 24/7; as long as you scan at least once every 8 hours, you get a full, continuous data set, without having to remember to check repeatedly during that time.
Second, this continuous data set means that you not only know where you are in terms of your glucose level, you also know where you’ve been, and the path that got you there. For example, when my son’s BG is, say, 16.5, the first question in my mind is, “Why?” If I look at back-data and see an in-range plateau in the morning, followed by a steady climb in the two hours after lunch, then I may suspect that the lunch insulin-to-carb ratio is too weak. If, on the other hand, I see an in-range plateau in the morning, followed by a sudden drop after lunch, followed by a steep climb, then I may suspect that the lunch insulin-to-carb ratio is too strong. These very different scenarios will lead me to take opposite actions to prevent similar high BG tomorrow, and I don’t know which one is the better strategy unless I've seen that back-data to inform my decision.
In addition, this recent glucose history allows for real-time trend information, that tells you whether your glucose is steady, dropping, or rising . When you see a reading of 5.5 mmol/L, you may wonder, “Will my glucose stay steady at 5.5? Will it drop over the next several minutes? Or will it rise?” These different glucose trends will lead you to different actions. If glucose is falling, you may decide to eat to prevent a low. If glucose is rising you may want to avoid eating and check back in a half hour to make sure it hasn’t skyrocketed. If glucose is steady, you may relax, knowing you don’t need to take any action right now. In each case, your response is influenced by the trend information made possible by the back-data.
(*In case you’re curious, in terms of back data, the system stores the single reading that occurs at the 15-minute point, not the average of all the readings over that time period. For trend information, however, the system uses all the data from the previous 15 minutes. And for the current glucose reading, the system displays the actual reading at the moment that you scan, in real-time, NOT the reading at the beginning of the current 15-minute interval.)
4. Long Sensor Life
You can use a Libre/Libre 2 sensor for 14 consecutive days (vs 7 or 10 days for CGM sensors), the longest sensor life for any glucose monitoring system currently available in Canada. This could mean half as many or a third fewer insertions compared to a CGM system, saving you time, money and mental energy.
5. Lower Financial Cost (vs. CGM)
The ongoing cost to use Libre/Libre 2 is much lower than that of CGM systems, and there is no annual commitment involved with the system pricing. See Comparing CGM / Flash Systems for details.
6. Accuracy
Accuracy is a bit of a complex issue when it comes to both Flash Glucose Monitoring and CGM. How do we assess accuracy? To start, what external measure do we use to judge this? Research studies on CGM accuracy often use a lab analyzer blood glucose value as a comparison, and measure how well a collection of sensor readings match those lab BG values. I haven’t been able to find similar research published in Canada on Flash Glucose Monitoring. However, I understand (anecdotally) that in order to receive Health Canada approval, data from the Libre system would have had to be compared with a device with proven accuracy: in this case that’s the Yellowsprings instrument, a frequently used and well-established glucose analyzer. In addition, there are published studies out of the United States which support its accuracy, including one sponsored by Abbott Diabetes Care (manufacturers of the Freestyle Libre) which indicates that “interstitial glucose measurements with the FreeStyle Libre system were found to be accurate compared with capillary BG reference values, with accuracy remaining stable over 14 days of wear” ¹
The nitty gritty details from that study: “The accuracy of the results was demonstrated against capillary BG reference values, with 86.7% of sensor results within Consensus Error Grid Zone A” (Zone A is defined as having “no effect on clinical action”) Further, “the overall mean absolute relative difference was 11.4%.”
Translation: When compared with capillary BG reference values – ie. Fingerstick results using a blood glucose meter – over 86% of the Libre test readings were close enough to the meter readings such that the user would not have taken a different action based on the Libre results than they would have taken based on the meter results. Also, the average difference between the Libre readings and meter readings was about 11%.
A similar study from the UK ² supported the accuracy of the Libre for children and teens (age 4-17 years old): “Clinical accuracy of sensor results versus BG results was demonstrated, with 83.8% of results in zone A and 99.4% of results in zones A and B of the consensus error grid. Overall mean absolute relative difference (MARD) was 13.9%.
What does this mean? Does this mean that the Libre was more accurate than the meter, or that the meter was more accurate than the Libre? We have no real way of knowing, as meters can also be “out” by 10-15% and still be considered accurate by current standards. Further, we need to keep in mind that the 2 readings actually measure different things: the sensor measures the glucose in the interstitial fluid, while the lab result measures the glucose in the blood. In truth, these measures may not match at a moment in time, and further, they don’t have to match for each of them to be correct in their own right. But does that matter in our real-life use of diabetes tech?
Maybe the real question from real people with diabetes is: how can I be confident that the sensor is accurate?
Or in other words... Can I trust the sensor?
How do we measure accuracy?
For my own information, I used our tried and true, lab-verified blood glucose meters as a basis of comparison. After all, the clinical recommendations offered by Diabetes Canada and by our son’s endocrinologist, as well as our experience with diabetes over the past several years, have all been based on blood glucose values. The treatment decisions we make are based on blood glucose. So for the Flash Glucose system to be useful in real-life, it should at least approximate those blood glucose values (taking into account lag-time, explained below), even though it’s getting there via a different measurement path.
For us, the Libre system seemed to do that very well: the sensor results resembled the meter results most of the time, and we didn't have any problems by acting on the the sensor results. In short, we trust the Libre.

What about Lag time?
Glucose shows up in the blood first. Via the blood, it moves around the body and out into the surrounding tissue and organs. This process of movement into the tissue takes time to occur, creating a lag between blood glucose and the glucose in the interstitial fluid where the sensor measures glucose. This lag time occurs both when glucose is increasing (such as when we eat, or when the liver releases stored glucose) as well as when it’s decreasing (when insulin is active, or as a result of exercise, when glucose is drawn out of the blood to feed the muscles).
From the Freestyle Libre website:
“Glucose levels can be measured from the bloodstream, or from the interstitial fluid (ISF), the fluid which surrounds the body’s cells, as glucose freely diffuses from capillaries to the interstitial space³. ISF glucose and BG measurements taken simultaneously won’t always match, and, in fact, are likely to be different. There is a 5- to 10-minute delay in ISF glucose response to changes in blood glucose4 which is unlikely to impact routine day-to-day treatment decisions. The average lag time of the FreeStyle Libre system is approximately 5 minutes5 ”
With the newer Libre 2 technology lag-time has been reduced to 2 minutes, which is part of why you can make treatment decisions based on the Libre 2 sensor glucose reading.
What Does Lag Time Mean in Real-life?
In short:
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When glucose is rising, the current sensor glucose (SG) reading will be lower than the current blood glucose (BG) reading (but similar to the BG reading from 2-10 minutes before).
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When glucose is falling, the current sensor glucose (SG) reading will be higher than the current blood glucose (BG) reading (but similar to the BG reading from 2-10 minutes ago).
So if you feel the symptoms of a low, but the sensor says your glucose is in-range, it’s wise to double-check using a blood glucose meter.
Other Benefits of Libre/Libre 2:
The insertion of the sensor is painless for many people (I didn’t even feel it at all; my son did, but said it “wasn’t that bad”) and simple: each sensor comes with a disposable applicator in the package; you load the sensor into the applicator, place the applicator against your skin, and press down firmly… the applicator inserts the sensor for you at the correct depth and angle. As one RN/CDE shared, the action and pressure are similar to what you would do to use a self-inking stamp. And for kids who may be easily spooked, the applicator looks less intimidating than some CGM inserters.
The dedicated Libre/Libre 2 reader has a touch screen and is straight-forward to use: it has only 1 button (to turn it on), the rest of the functions are accessed by pressing icons on the screen. This means even young children (and tech-confused adults!) can check their glucose independently.
The backlit screen can be read in dim lighting, in the dark of a movie theatre, or at your child’s bedside in the middle of the night.
The ability to use a smartphone and Libre 2 app makes Libre 2 even more convenient.
The dedicated Libre/Libre 2 reader functions as a scanner for the sensor, as a fingerstick blood glucose meter AND as a blood ketone tester (using different test strips for each of these functions), reducing the number of devices to lug around. This simplicity is a huge benefit from my perspective!
The dedicated Libre/Libre 2 reader includes a Rapid-Acting Insulin Calculator, which suggests insulin doses based on meter results (not sensor readings) and the insulin ratios entered into the system by an authorized health care provider. (You cannot set this function up on your own; a health care provider’s security code is needed to access this function.) In this way, the device will “do the math for you” to correct above-target BG and to cover carb-containing food. This is especially valuable for individuals on injected insulin programs, as this “bolus calculation” provides a kind of bridge to the functions of an insulin pump.
The sensor is water-resistant (IP27: can withstand immersion in up to one metre (3 feet) of water for up to 30 minutes) and so can be worn while bathing, showering, swimming or exercising. (For tips on reducing the chance that the sensor will fall off, check out Skin Prep Products to Keep Sensors On and 14 Strategies to Keep Sensors On.) The reader is not water-resistant, though, so you’ll want to protect it from exposure.
The sensor housing has a fairly low profile (5mm high with a flat surface) and relatively small diameter (35mm), making the unit about the size of a toonie, which is pretty discreet in the world of diabetes technology. The reader is also a reasonable size and lightweight.
Summary data is available in the app, on the Libre/Libre 2 reader, or if you want to dig even deeper, data can be transferred to Diasend, or to LibreView, a secure, cloud-based diabetes management system that gives healthcare professionals and patients clear, easy-to-understand reports from compatible FreeStyle glucose monitoring devices.
You can add Notes to the data. There are 5 standard notes (Food, Exercise, Illness, Rapid-Acting Insulin Dose, and Basal Insulin Dose), plus you can set up to 6 more personalized notes for things like eating out, alcohol, intense exercise, missed bolus, or whatever variable that you would personally like to keep track of.
Limitations of Libre:
Whether you consider a particular feature (or lack thereof) a drawback of a particular technology depends on your perspective, and the Libre is no different in that regard. A “good” tool is one that matches your needs and objectives. The following qualities of Flash Glucose Monitoring may make it a mismatch for some people:
1. Possible Skin Reactions
Although most people do not have problems with the materials that make up the sensor housing or adhesive patch, some people do. And if you’re one of those people who experiences a rash, itching, even blistering at the insertion site, it can be uncomfortable. For some people, the reaction is significant enough that they can no longer use this tech tool.
Tips from the Trenches
Unfortunately for us, our son is one of those users whose skin reacted to the sensor materials. In the first day after we inserted the sensor, he told me it was a bit itchy. But the itch wasn’t new to him; he used to develop quite a maddening itch to Dexcom sensors before, too. After that first day with the Libre, he no longer complained of itching. And the sensor accuracy couldn’t be beat, so it seemed that all was going well. Until Day 6, when he told me there was liquid coming out of his sensor. It seemed odd that the fluid was yellow, so we decided to investigate. When he took the patch off, the entire area under it was red and blistered. Some of the blisters had broken, which was where the fluid was coming from. Once exposed to the air, the area was painful, and took several days to heal. His body’s reaction means that now we take steps to protect the skin and prevent the reaction in order to keep using the Libre system.
It’s interesting to note that when I wore a sensor, I had absolutely no adverse skin reactions. This just goes to show, once again, that individual experiences will vary.
-Michelle
2. Financial Cost (vs. test strips)
If you compare the price of a Libre/Libre 2 sensor to that of test strips for the same usage period (14 days), and you are routinely doing less than 8 glucose checks per day, you may feel that the cost of using the Libre is high. (Assuming a sensor cost of CA$97 each and an average test strip cost of CA$0.75/strip). But once again, it’s all about perspective...
If you usually check BG more than 8 times per day (as our son does), using the Libre will actually cost less than test strips (assuming you use it to the end of the sensor life, or 14 days). Additionally, if you factor in the potential to perform countless glucose “scans”, plus access to over 1300 stored glucose measurements over that period (based on the fact that the system stores the glucose reading every 15 minutes, or 96 times each day), then you may consider the cost of using the system to be quite low. Finally, compared to the cost of using Continuous Glucose Monitoring (with a greater initial cost for the CGM receiver, and CGM sensors priced approximately the same but not lasting as long), flash glucose monitoring comes in at a lower operational cost. Once again, the cost-benefit analysis creates a different “right” decision for different people. My hope is that by reading this information, both pros and cons, you will be in a position to make a decision that fits for your family.
Tips from the Trenches
I believe that part of the cost-benefit analysis includes non-monetary factors, including the emotional relief that some d-devices offer. My 10-year-old son has had type 1 diabetes for over 9 years now, and at this point is worn out by the demands of diabetes care. When he recently tried out the Libre system, for the first time ever he actually got excited about something related to diabetes. His face lit up when he realized that, to check his blood sugar, all he had to do was scan. And because we have found consistent accuracy with the Libre, I trust the readings, so we rarely need to add backup BG meter checks when he’s wearing a sensor. In his case, using the Libre truly does replace most of the fingerpokes. So if the system similarly eases the burden of diabetes for your family, and if that’s an objective for you, you may also feel it’s worth the dollars and cents.
-Michelle
3. No Alerts (original Libre System)
If you’re looking for a glucose monitoring system that lets you know when your glucose is low (or high, or dropping/rising quickly) then the original Libre may not be the tool for you. Like CGM, Libre measures your glucose levels continuously without you having to think about it, but unlike Continuous Glucose Monitoring, Libre doesn’t give you feedback about your current glucose level until you scan the sensor. So if your child doesn’t recognize his own lows, or if playing on the iPad distracts him from feeling the symptoms, then it won’t provide a safety net for catching undetected low glucose.
Alerts ARE available with the newer Libre 2 system (see Benefits, above) but you still have to scan to find out the actual glucose reading.
Other Possible Limitations of Libre:
While CGM systems provide glucose info at a glance, without any additional action on your part after inserting the sensor, you still need to scan the sensor/transmitter in a Libre/Libre 2 systems in order to access the glucose reading, trends and recent history.
The Libre system doesn’t allow pairing of more than one reader with the same sensor, so there’s no point in purchasing a backup reader to store at school for those times that your child forgets to bring the paired reader. If you’re in the habit of stashing backup meters in all the usual places, then you’ll have to continue using BG meters for that purpose. (Although the reader does also function as a BG meter, so with a few stashed around, you have meter backups that use the same strips.)
Although Libre 2 (available in Canada soon) gives you the choice to use either a dedicated Libre 2 reader or your smartphone with the Freestyle Libre 2 app, the sensor will only communicate with the one device that was used to start the sensor session.
You can’t toss the BG meter just yet. Although you can use Libre 2 to make treatment decisions (dose insulin for above-target SG and take low treatment for low SG), according to the Freestyle Libre User’s Manual, you should use a blood glucose meter to confirm the sensor reading when:
- BG is rising or falling quickly (↑ or ↓ trend arrows), as the interstitial fluid levels don’t accurately reflect blood glucose levels at that moment because of lag time.
- glucose is low, or headed for a low… it’s wise to confirm the reading before treating.
- your symptoms don’t match the flash glucose monitor reading.
Accuracy of the glucose readings may be reduced in the first day after insertion. This isn’t a limitation of the technology, but instead is the result of a typical physiological response. Our bodies tend not to like having extra things on or in them. As a result, there may be an initial inflammation response to the presence of the sensor wire underneath the skin, which may affect the accuracy of the glucose readings for several hours after insertion. The Abbott website points out: “Sensors tend to give lower and more variable glucose readings on day 1 of Sensor wear since it takes some time for your body to adjust to a newly inserted sensor”. During this time, it would be wise to verify the glucose readings using a blood glucose meter, especially when making treatment decisions based on the current glucose level (treating a low or delivering insulin to correct a high).
Tips from the Trenches
For my son (10-year old with T1D) the sensor was accurate right from start-up (80% of the times that we did a fingerstick check as comparison, the sensor reading was within 15% of the BG meter result).
For me (adult, not T1D) this adjustment period actually lasted 2 days.
-Michelle
References:
Bailey, T., Bode, B. W., Christiansen, M. P., Klaff, L. J., & Alva, S. (2015). The Performance and Usability of a Factory-Calibrated Flash Glucose Monitoring System. Diabetes Technology & Therapeutics, 17(11), 787–794. http://doi.org/10.1089/dia.2014.0378
Edge, J., Acerini, C., Campbell, F., Hamilton-Shield, J., Moudiotis, C., Rahman, S., … Trevelyan, N. (2017). An alternative sensor-based method for glucose monitoring in children and young people with diabetes. Archives of Disease in Childhood, 102(6), 543–549. http://doi.org/10.1136/archdischild-2016-311530
Rebrin K, Steil GM. Can interstitial glucose assessment replace blood glucose measurements? Diabetes Technol Ther. 2000;2(3):461-472.
Rebrin K, Sheppard NF Jr, Steil GM. Use of subcutaneous interstitial fluid glucose to estimate blood glucose: revisiting delay and sensor offset. J Diabetes Sci Technol. 2010;4(5):1087-1098.
Data on File, Abbott Diabetes Care Inc, Clinical Report: Evaluation of the Accuracy of the Abbott Sensor-Based Interstitial Glucose Monitoring System 2014.
Also
- The Freestyle website, Libre 2 page
- Freestyle Libre Flash Glucose Monitoring System User’s Manual, 2017
- Abbott FreeStyle website, Libre page
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